Position: Postdoctoral Fellow
Phone: +47 77644716
Fax: +47 77645350
E-mail: malachy@fagmed.uit.no
 

Dr. Malachy Ifeanyi Okeke jobber med sitt postdoktorat ved GenØk – Senter for biosikkerhet. Han fikk sin doktorgrad fra Universitetet i Tromsø i 2007, hvor han karakteriserte rekombinante virus fra in vitro rekombinasjon mellom transgene of villtype orthopoxvirus. Den nåværende forskningen til Dr. Okeke fokuserer på virus-virus mellom transgene og villtype orthopoxvirusog deres mammalske verter. Forskningen fokuserer også på hvordan disse interaksjonene kan resultere i potensielle problemer med biosikkerhet, spesielt om transgene poxvirus brukes som vaksine for humane- og dyresykdommer.


Publications: 2000 – Date

Okeke M.I, Hansen H, and Traavik T. (2011). A naturally occurring cowpox virus with an ectromelia virus A-type inclusion protein gene displays atypical A-type inclusions. Infect Genet Evol, Sep 29 [Epub ahead of print], doi:10.1016/j.meegid.2011.09.017.

Tryland M., Okeke M.I., Hård af Segerstad C., Mörner T., Traavik T., Ryser-Degiorgis M-P.2011. Orthopoxvirus DNA in Eurasian lynx, Sweden. Emerging Infectious Diseases 17(4), 626-632. http://www.cdc.gov/eid/content/17/4/626.htm

Okeke, M.I., Adekoya, A.O., Moens, U., Tryland, M., Traavik, T. and Nilssen Ø. (2009). Comparative sequence analysis of A-type inclusion (ATI) and P4c proteins of orthopoxviruses that produce typical and atypical ATI phenotypes. Virus Genes 39, 200-209.

Hansen, H., Okeke, M.I., Nilssen, Ø. and Traavik, T. (2009). Comparison and phylogenetic analysis of cowpox viruses isolated from cats and humans in Fennoscandia. Arch Virol 154, 1293-1302.

Okeke, M.1., Nilssen, Ø., Moens, U., Tryland, M. and Traavik, T. (2009). In vitro host range, multiplication and virion forms of recombinant viruses obtained from co-infection in vitro with a vaccinia-vectored influenza vaccine and a naturally occuring cowpox virus isolate. Virol J. 6:55.

Okeke M. I. (2007). Recombination in vitro between transgenic and wild type orthopoxviruses; characterization of parental and progeny hybrid viruses. Ph.D Thesis. University of Tromsø, Norway. ISBN:978-82-7589-188-2 .

Okeke M. I., Nilssen Ø, and Traavik T. (2006). Modified vacinia virus Ankara (MVA) multiplies in rat IEC-6 cells and limited production of mature virions occurs in other mammalian cell lines. J Gen Virol 87, 21-27.

Hansen H, Okeke M. I, Nilssen Ø, and Traavik. T. 2004. Recombinant viruses obtained from co-infection in vitro with a live vaccinia-vectored influenza vaccine and a naturally occurring cowpox virus display different plaque phenotypes and loss of the transgene. Vaccine 23, 499-506.

Weli S. C, Okeke M. I, Tryland M, Nilssen Ø and T. Traavik. 2004. Characterization of Avipoxviruses from wild birds in Norway. Canadian Journal of Veterinary Research 68(2), 140-145.

Okoli A. S, Okeke M. I, Iroegbu C.U and Ebo P. U. 2002. Antibacterial activity of Harungana madagascariensis leaf extract. Phytotherapy Research 16(2), 174-179.

Okeke M. I, Iroegbu C.U, Eze E.N, Okoli A. S and Esimone C.O. 2001. Evaluation of extracts of the root of Landolphia owerrience for antibacterial activity. Journal of Ethnopharmacology 78, 119-127.

Okeke M.I., Iroegbu C.U., Jideofor C.O., Okoli A.S. and Esimone C.O. 2001. Antimicrobial activity of ethanol extracts of two indigenous nigerian spices. Journal of Herbs, Spices, and Medicinal plants 8(4), 39-46.

Okeke M.I., Iroegbu C.U. and Nwadinobi G.C. 2000. Cultural conditions affecting the production of Beta-haemolysin of Bacillus globisporus. Global Journal of Pure and Applied Sciences 6(2), 215-219.